Oral Semaglutide Prices Compared: $99 to $299 Across 12 Providers

Oral semaglutide pricing spans a wide range in July 2026 — from $99/mo compounded sublingual programs up to $349/mo for brand-name Foundayo at the highest dose tier. The number alone doesn't tell you much, though, since these aren't interchangeable products: an FDA-approved tablet and a compounded sublingual drop can carry the same monthly price and deliver very different amounts of active drug into your bloodstream.

Here's the full list, cheapest to most expensive, with format and type called out so you're comparing apples to apples.

⚠️ MEDVi has received an FDA warning letter regarding marketing practices. † Wellorithm's oral/sublingual format is still being confirmed directly with the provider — treat this listing as reported, not verified.

The Budget Tier: Under $200/mo

MadeMed leads on price with sublingual semaglutide starting at $99/mo, and it's LegitScript certified. Zealthy's $151/mo capsule pricing is billed quarterly rather than monthly, so budget for the upfront cost even though the effective monthly rate is competitive. Direct Meds and Eden Health both sit in the $179–$249 range depending on dose and month.

The Mid Tier: $200–$250/mo

SkinnyRx, SHED, and MEDVi cluster in this range. SHED's price is worth flagging specifically: it starts around $229/mo but jumps to $399/mo once you're titrated up to 7.5mg or higher — a real cost that's easy to miss if you're only looking at the starting-dose number. MEDVi has received an FDA warning letter over its marketing practices; that's a compliance issue with the company, not necessarily a statement about the product itself, but it's worth knowing before you sign up.

The FDA-Approved Tier: $149–$349/mo

Foundayo's LillyDirect self-pay pricing actually overlaps with the compounded tier at the entry dose ($149/mo for 0.8mg), climbing to $299–$349/mo at the higher maintenance doses used for meaningful weight loss. The Wegovy pill, accessed through providers like Sesame Care, follows a similar dose-tiered structure. Both come with published clinical trial data behind the exact dose you're taking — something none of the compounded options can currently offer.

How to Actually Compare These

Price per month is the easiest number to compare and the least useful one on its own. Before picking based on price alone, check:

• What dose you're actually being quoted for. Starting-dose pricing and maintenance-dose pricing can differ by $100+/mo, as with SHED.
• Whether the format has any published absorption data. SNAC-based tablets do; most sublingual drops and dissolvable tablets don't.
• Billing cadence. Zealthy's pricing is quarterly, not monthly — know your total upfront cost.
• Company compliance history. A provider's FDA warning-letter status is public record and worth a quick search before you commit.

For the tirzepatide side of this market — which is a meaningfully different scientific story — see our oral tirzepatide guide. And if you're trying to decide between the FDA-approved pills and the compounded route specifically, our head-to-head comparison walks through the trade-offs in more depth.